You can press the button that is Example. Moreover, you should decide thd siRNA's length and siRNA design rules.

Result of siRNA candidates

You will get the candidates for siRNAs. And you can check the box and select the database that you have an interest in list to blast the off-target. You should wait the few time for results.

Result of off-target testing

You can get the results that blast the database. Moreover, you can click the link to show the result.