Introduction

Small Ubiquitin-like Modifier ( SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. Sumoylation is a post-translational modification involved in various cellular processes, such as gene expression, DNA repair, chromosome assembly, and cellular signaling.

Recently, most sumoylation prediction tools are using algorism, protein physicochemical and biochemical properties or consensus motif to predict modification sites. But those tools rarely mention to the effect of other post translational modification (PTM) on sumoylation prediction.

We develop a sumoylation prediction tool considered other PTM with support vector machine and name it SUMOgo.